منابع مشابه
Modeling Protein Folding Pathways
Proteins fold through a series of intermediate states called a pathway. Protein folding pathways have been modeled using either simulations or a heirarchy of statistical models. Here we present a series of related statistical models that attempt to predict early, middle and late intermediates along the folding pathway. Isites motifs are discrete models for folding initiation sites. HMMSTR is a ...
متن کاملProtein Folding In Vivo: Unraveling Complex Pathways
polypeptides and rebinding of nonnative species in the central cavity of GroEL (reviewed by Fenton and HorFolding of proteins in a test tube is a private affair. wich, 1997). Protein folding in a cell is another matter entirely. In the For a number of years the predominant model for an complex milieu of the cell, the conditionsof temperature, in vivo protein folding pathway has been the sequent...
متن کاملPhysical Modeling of Protein Folding
Key words Classification system and/or index terms (if any) Supplementary bibliographical information Language ISSN and key title ISBN Recipient's notes Number of pages Price Security classification Distribution by (name and address) I, the undersigned, being the copyright owner of the abstract of the above-mentioned dissertation, hereby grant to all reference sources the permission to publish ...
متن کاملModeling two-state cooperativity in protein folding.
A protein model with the pairwise interaction energies varying as the local environment changes, i.e., including some kind of collective effect between the contacts, is proposed. Lattice Monte Carlo simulations on the thermodynamical characteristics and free energy profile show a well-defined two-state behavior and cooperativity of folding for such a model. As a comparison, related simulations ...
متن کاملModeling of Protein Folding and Genetic Networks
Key words Classification system and/or index terms (if any) Supplementary bibliographical information Language ISSN and key title ISBN Recipient's notes Number of pages Price Security classification Distribution by (name and address) I, the undersigned, being the copyright owner of the abstract of the above-mentioned dissertation, hereby grant to all reference sources the permission to publish ...
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ژورنال
عنوان ژورنال: Biology Direct
سال: 2018
ISSN: 1745-6150
DOI: 10.1186/s13062-018-0217-6